Tadamitsu KISHIMOTO: search on Z-Library

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1

Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis

Tomoyuki Imagawa, Shumpei Yokota, Masaaki Mori, Takako Miyamae, Syuji Takei, Hiroyuki Imanaka, Yasuhito Nerome, Naomi Iwata, Takuji Murata, Mari Miyoshi, Norihiro Nishimoto, Tadamitsu Kishimoto

Journal:

Modern Rheumatology

Year:

2012

Language:

english

File:

PDF, 368 KB

english, 2012

2

Therapeutic Targeting of the Interleukin-6 Receptor

Tanaka, Toshio, Narazaki, Masashi, Kishimoto, Tadamitsu

Journal:

Annual Review of Pharmacology

Year:

2012

Language:

english

File:

PDF, 811 KB

english, 2012

3

Targeting Interleukin-6 Signaling in Clinic

Kang, Sujin, Tanaka, Toshio, Narazaki, Masashi, Kishimoto, Tadamitsu

Journal:

Year:

2019

Language:

english

File:

PDF, 1.89 MB

english, 2019

4

INTERLEUKIN-6: From Basic Science to Medicine—40 Years in Immunology

Kishimoto, Tadamitsu

Journal:

Annual Review of Immunology

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

5

Cytokine signal transduction

Tadamitsu Kishimoto, Tetsuya Taga, Shizuo Akira

Journal:

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

6

Interleukin (IL-6) Immunotherapy

Tanaka, Toshio, Narazaki, Masashi, Kishimoto, Tadamitsu

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2017

Language:

english

File:

PDF, 958 KB

english, 2017

7

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

Shizuo Akira, Yukihiro Nishio, Masahiro Inoue, Xue-Jie Wang, Shi We, Taiji Matsusaka, Kanji Yoshida, Tetsuo Sudo, Masanobu Naruto, Tadamitsu Kishimoto

Journal:

Year:

1994

Language:

english

File:

PDF, 1.76 MB

english, 1994

8

Session Chair Comments

TADAMITSU KISHIMOTO

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 90 KB

english, 1989

9

Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL 6 monoclonal antibodies

Tadashi Matsuda, Toshio Hirano And, Tadamitsu Kishimoto

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 766 KB

english, 1988

10

Anti–interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis

Hideko Nakahara, Jian Song, Masamichi Sugimoto, Keisuke Hagihara, Tadamitsu Kishimoto, Kazuyuki Yoshizaki, Norihiro Nishimoto

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

11

Impaired immune and acute-phase responses in interleukin-6-deficient mice

Kopf, Manfred, Baumann, Heinz, Freer, Giulia, Freudenberg, Marina, Lamers, Marinus, Kishimoto, Tadamitsu, Zinkernagel, Rolf, Bluethmann, Horst, Köhler, Georges

Journal:

Year:

1994

File:

PDF, 449 KB

1994

12

A Novel Role for STAT3 in Cardiac Remodeling

Keiko Yamauchi-Takihara, Tadamitsu Kishimoto

Journal:

Trends in Cardiovascular Medicine

Year:

2000

Language:

english

File:

PDF, 222 KB

english, 2000

13

Functional expression of a microinjected Edα gene in C57BL/6 transgenic mice

Yamamura, Ken-ichi, Kikutani, Hitoshi, Folsom, Virginia, Clayton, Linda K., Kimoto, Masao, Akira, Shizuo, Kashiwamura, Shin-ichiro, Tonegawa, Susumu, Kishimoto, Tadamitsu

Journal:

Year:

1985

File:

PDF, 375 KB

1985

14

Molecular cloning and expression of an IL-6 signal transducer, gp130

Masahiko Hibi, Masaaki Murakami, Mikiyoshi Saito, Toshio Hirano, Tetsuya Taga, Tadamitsu Kishimoto

Journal:

Year:

1990

Language:

english

File:

PDF, 1.34 MB

english, 1990

15

Biological and clinical aspects of interleukin 6

Toshio Hirano, Shizuo Akira, Tetsuya Taga, Tadamitsu Kishimoto

Journal:

Immunology Today

Year:

1990

Language:

english

File:

PDF, 2.61 MB

english, 1990

16

Reply

Toshio Tanaka, Ichiro Kawase, Tadamitsu Kishimoto

Journal:

Arthritis Care & Research

Year:

2010

Language:

english

File:

PDF, 54 KB

english, 2010

17

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

Minoru Fujimoto, Satoshi Serada, Masahiko Mihara, Yasushi Uchiyama, Hiroto Yoshida, Nobuo Koike, Yoshiyuki Ohsugi, Teppei Nishikawa, Barry Ripley, Akihiro Kimura, Tadamitsu Kishimoto, Tetsuji Naka

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 405 KB

english, 2008

18

Functional V region formation during in vitro culture of a murine immature B precursor cell line

Sugiyama, Haruo, Akira, Shizuo, Kikutani, Hitoshi, Kishimoto, Susumu, Yamamura, Yuichi, Kishimoto, Tadamitsu

Journal:

Year:

1983

File:

PDF, 601 KB

1983

19

gp130 signaling pathways: Recent advances and implications for cardiovascular disease

Hisao Hirota, Kanji Yoshida, Tetsuya Taga, Tadamitsu Kishimoto

Journal:

Trends in Cardiovascular Medicine

Year:

1996

Language:

english

File:

PDF, 4.32 MB

english, 1996

20

Negative regulation of cytokine signaling: STAT-induced STAT inhibitor

Tetsuji Naka, Minoru Fujimoto, Tadamitsu Kishimoto

Journal:

Trends in Biochemical Sciences

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

21

Studies on the structure and regulation of the human hepatic interleukin-6 receptor

Stefan ROSE-JOHN, Heidi SCHOOLTINK, Dorothée LENZ, Erich HIPP, Gabi DUFHUES, Hildegard SCHMITZ, Xaver SCHIEL, Toshio HIRANO, Tadamitsu KISHIMOTO, Peter C. HEINRICH

Journal:

Year:

1990

Language:

english

File:

PDF, 559 KB

english, 1990

22

Differential shedding of the two subunits of the interleukin-6 receptor

Jürgen Müllberg, Elke Dittrich, Lutz Graeve, Claudia Gerhartz, Kiyoshi Yasukawa, Tetsuya Taga, Tadamitsu Kishimoto, Peter C. Heinrich, Stefan Rose-John

Journal:

Year:

1993

Language:

english

File:

PDF, 750 KB

english, 1993

23

Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma

Shun Kitaba, Hiroyuki Murota, Mika Terao, Hiroaki Azukizawa, Fumitaka Terabe, Yoshihito Shima, Minoru Fujimoto, Toshio Tanaka, Tetsuji Naka, Tadamitsu Kishimoto, Ichiro Katayama

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 2.72 MB

english, 2012

24

PS2-09 The deficiency of thymus fails to improve lethal inflammation in SOCS-1 knockout mice

Tomohiro Ukita, Minoru Fujimoto, Yongmei, Hirohisa Kawabata, Tadamitsu Kishimoto, Tetsuji Naka

Journal:

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

25

Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production

Millrine, David, Tei, Mami, Gemechu, Yohannes, Kishimoto, Tadamitsu

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1018 KB

english, 2016

26

T15-Idiotype Positive, IgE Class-Specific Suppressor T Cells and Characterization of the Suppressor Factor

Kishimoto, Tadamitsu, Sugimura, Kazuhisa, Suemura, Masaki, Shiho, Osamu, Maeda, Keiji, Yamamura, Yuichi, Böttcher, Irmgard

Journal:

International Archives of Allergy and Immunology

Year:

1981

Language:

english

File:

PDF, 759 KB

english, 1981

27

Discovery of IL-6 and Development of Anti-IL-6R Antibody

Kishimoto, Tadamitsu

Journal:

The Keio Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 257 KB

english, 2019

28

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

Toshio Hirano, Tadashi Matsuda, Martin Turner, Nobuyuki Miyasaka, Glenn Buchan, Bo Tang, Kazuto Sato, Masatoshi Shimi, Ravinder Maid, Marc Feldmann, Tadamitsu Kishimoto

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 808 KB

english, 1988

29

Induction of rat acute-phase proteins by interleukin 6 in vivo

Thomas Geiger, Tilo Andus, Jan Klapproth, Toshio Hirano, Tadamitsu Kishimoto, Peter C. Heinrich

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 703 KB

english, 1988

30

Homotypic aggregation of murine B lymphocytes is independent of CD23

Edward J. Davey, William C. Bartlett, Hitoshi Kikutani, Hiroshi Fujiwara, Tadamitsu Kishimoto, Daniel H. Conrad, Eva Severinson

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 919 KB

english, 1995

31

Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration

Ekihiro Seki, Hiroko Tsutsui, Yuji Iimuro, Tetsuji Naka, Gakuhei Son, Shizuo Akira, Tadamitsu Kishimoto, Kenji Nakanishi, Jiro Fujimoto

Journal:

Year:

2005

Language:

english

File:

PDF, 349 KB

english, 2005

32

SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells

Xinshou Ouyang, Minoru Fujimoto, Reiko Nakagawa, Satoshi Serada, Toshio Tanaka, Shintaro Nomura, Ichiro Kawase, Tadamitsu Kishimoto, Tetsuji Naka

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 373 KB

english, 2006

33

High Sensitivity to Peripheral Blood Lymphocytes and Low HLA-class I Antigen Expression of Small Cell Lung Cancer Cell Lines with Diverse Chemo-radiosensitivity

Yoshiro Tanio, Masatoshi Watanabe, Tadashi Osaki, Isao Tachibana, Ichiro Kawase, Taro Kuritani, Shin'ichi Saito, Tomiya Masuno, Nagahisa Kodama, Kiyoyuki Furuse, Tadamitsu Kishimoto

Journal:

Year:

1992

File:

PDF, 618 KB

1992

34

Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells

Floege, Jürgen, Topley, Nicholas, Wessel, Klaus, Kaever, Volkhard, Radeke, Heinfried, Hoppe, Jürgen, Kishimoto, Tadamitsu, Resch, Klaus

Journal:

Kidney International

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

35

Signal transducer and activator of transcription protein (STAT): Its relation to Th1/Th2-mediated diseases

Kiyoshi Takeda, Tadamitsu Kishimoto, Shizuo Akira

Journal:

Year:

1997

Language:

english

File:

PDF, 247 KB

english, 1997

36

Identification of a Transcriptional Regulatory Factor for Human Aromatase Cytochrome P450 Gene Expression as Nuclear Factor Interleukin-6 (NF-IL6), a Member of the CCAAT/Enhancer-Binding Protein Family

Katsumi Toda, Shizuo Akira, Tadamitsu Kishimoto, Hiroshi Sasaki, Kozo Hashimoto, Yasutake Yamamoto, Yusuke Sagara, Yutaka Shizuta

Journal:

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

37

Universal Skew of T Cell Receptor (TCR) Vβ Usage for Crohn's Disease (CrD)

Hiroyuki Ogawa, Hiroaki Ito, Akira Takeda, Sumie Kanazawa, Mitsunari Yamamoto, Hideji Nakamura, Yoshihiro Kimura, Kazuyuki Yoshizaki, Tadamitsu Kishimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 136 KB

english, 1997

38

gp130-DEPENDENT SIGNALLING PATHWAY IS NOT ENHANCED IN gp130 TRANSGENIC HEART AFTER LIF STIMULATION

Eiroh Tone, Keita Kunisada, Atsushi Kumanogoh, Shinji Negoro, Masanobu Funamoto, Tomoaki Osugi, Tadamitsu Kishimoto, Keiko Yamauchi-Takihara

Journal:

Year:

2000

Language:

english

File:

PDF, 257 KB

english, 2000

39

The Development of AIDS-Associated Burkitt's/Small Noncleaved Cell Lymphoma Is Preceded by Elevated Serum Levels of Interleukin 6

Elizabeth Crabb Breen, Meta van der Meijden, William Cumberland, Tadamitsu Kishimoto, Roger Detels, Otoniel Martı&amp, #x0301, nez-Maza

Journal:

Clinical Immunology

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

40

Cytokine Signal Transduction through a Homo-or Heterodimer of gp130

TADAMITSU KISHIMOTO, TAKASHI TANAKA, KAMJI YOSHIDA, SHIZUO AKIRA, TETSUYA TAGA

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 546 KB

english, 1995

41

Detailed deletion mapping of the short arm of chromosome 3 in small cell and non-small cell carcinoma of the lung

Hosoe, Shigeto, Shigedo, Yoshihisa, Ueno, Kiyonobu, Tachibana, Isao, Osaki, Tadashi, Tanio, Yoshiro, Kawase, Ichiro, Yamakawa, Kazuhiro, Nakamura, Yusuke, Kishimoto, Tadamitsu

Journal:

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

42

Interleukin 6 Induces Secretion of IgG1 by Coordinated Transcriptional Activation and Differential mRNA Accumulation

Marie-Cécile Raynal, Ziying Liu, Toshio Hirano, Lloyd Mayer, Tadamitsu Kishimoto and Selina Chen-Kiang

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.39 MB

english, 1989

43

Impaired B-Lymphopoiesis, Myelopoiesis, and Derailed Cerebellar Neuron Migration in CXCR4- and SDF-1-Deficient Mice

Qing Ma, Dan Jones, Paul R. Borghesani, Rosalind A. Segal, Takashi Nagasawa, Tadamitsu Kishimoto, Roderick T. Bronson and Timothy A. Springer

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 2.04 MB

english, 1998

44

Osteoclasts Are Present in gp130-Deficient Mice 1

Kawasaki, Kojiro, Gao, Yu-Hao, Yokose, Satoshi, Kaji, Yoshio, Nakamura, Toshitaka, Suda, Tatsuo, Yoshida, Kanji, Taga, Tetsuya, Kishimoto, Tadamitsu, Kataoka, Hiroko, Yuasa, Takahito, Norimatsu, Hirom

Journal:

Year:

1997

Language:

english

File:

PDF, 1.50 MB

english, 1997

45

Functional Inhibition of Hematopoietic and Neurotrophic Cytokines by Blocking the Interleukin 6 Signal Transducer gp130

Tetsuya Taga, Masashi Narazaki, Kiyoshi Yasukawa, Takashi Saito, Daisuke Miki, Michinari Hamaguchi, Samuel Davis, Mohammed Shoyab, George D. Yancopoulos and Tadamitsu Kishimoto

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

46

Generation of Plasmacytomas with the Chromosomal Translocation t(12;15) in Interleukin 6 Transgenic Mice

Sachiko Suematsu, Taiji Matsusaka, Tadashi Matsuda, Shinsuke Ohno, Jun-ichi Miyazaki, Ken-ichi Yamamura, Toshio Hirano and Tadamitsu Kishimoto

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 792 KB

english, 1992

47

1. A New Era for Treatment of Intractable Immune Disorders

Kishimoto, Tadamitsu

Journal:

Nihon Naika Gakkai Zasshi

Year:

2014

File:

PDF, 144 KB

2014

48

Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy

Nishimoto, Norihiro, Sasai, Mitsuko, Shima, Yoshihito, Nakagawa, Masashi, Matsumoto, Tomoshige, Shirai, Toshikazu, Kishimoto, Tadamitsu, Yoshizaki, Kazuyuki

Journal:

Year:

2000

File:

PDF, 264 KB

2000

49

IL-6 receptor and mechanism of signal transduction

Tadamitsu Kishimoto, Shizuo Akira, Tetsuya Taga

Journal:

International Journal of Immunopharmacology

Year:

1992

Language:

english

File:

PDF, 529 KB

english, 1992

50

Demyelination in severe combined immunodeficient mice by intracisternal injection of cerebrospinal fluid cells from patients with multiple sclerosis: neuropathological investigation

H. Fujimura, Yuji Nakatsuji, Saburo Sakoda, Keiko Toyooka, Yoshinobu Okuda, Hiroo Yoshikawa, Misako Kaido, Yukihiko Saeki, Toru Mima, Tadamitsu Kishimoto, Takehiko Yanagihara

Journal:

Acta Neuropathologica

Year:

1997

Language:

english

File:

PDF, 1.83 MB

english, 1997

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